Enantioselection of amines using homocarbonates with hydrolase
US5981267A · kind A · utility
4Cited by
1References
23Claims
0Family size
Assignee
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Key dates
| Filing date | Jan 24, 1996 |
| Grant date | Nov 9, 1999 |
| Priority date | — |
| Expiry date | Jan 24, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P13/02
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Racemic amines are enzymically converted by enantioselective carbamation to produce to chiral carbamates. Simple homocarbonates employed as substrates. The chiral carbamates may then be deprotected to yield the original amine in a chiral form. Alternatively, the chiral carbamates may be reduced so as to produce methylated chiral amines.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.