Pyrazole derivatives and processes for the preparation thereof
US5981533A · kind A · utility
89Cited by
1References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 3, 1997 |
| Grant date | Nov 9, 1999 |
| Priority date | — |
| Expiry date | Oct 3, 2017 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
4-Amino-1H-pyrazolo[3,4-d]pyrimidine derivatives of formula I ##STR1## wherein the symbols are as defined in claim 1, and intermediates for their manufacture are described. The compounds of formula I inhibit especially the tyrosine kinase activity of the receptor for epidermal growth factor and can be used, for example, in the case of epidermal hyperproliferation (psoriasis) and as anti-tumor agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.