Neurokinin antagonists

US5985881A · kind A · utility

Assignee

• Boehringer Ingelheim GmbH · DE

Inventors

• Horst Dollinger · Schemmerhofen, DE
• Gerd Schnorrenberg · Ingelheim am Rhein, DE
• Hans Briem · Bremen, DE
• Birgit Jung · Laupheim, DE
• Georg Speck · Ingelheim am Rhein, DE

Key dates

• Filing date: Aug 2, 1997
• Grant date: Nov 16, 1999
• Expiry date: Aug 2, 2017

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2603/18
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to new compounds of general formula I ##STR1## and the pharmaceutically acceptable salts thereof, wherein A, B, Z, R.sup.1, R.sup.2, R.sup.3 and m are defined as in the specification, processes for preparing them and pharmaceutical compositions containing these compounds. The compounds are valuable neurokinin (tachykinin) antagonists.