Camptothecin compounds with combined topoisomarase I inhibition and DNA alkylation properties
US5985888A · kind A · utility
8Cited by
7References
5Claims
0Family size
Assignee
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Key dates
| Filing date | Nov 17, 1997 |
| Grant date | Nov 16, 1999 |
| Priority date | — |
| Expiry date | Nov 17, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D491/22
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Camptothecin compounds having a --CH.sub.2 --L group are effective anti-tumor compounds. These compounds inhibit the enzyme topoisomerase I and DNA of associated topoisomerase I-DNA complexes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.