Human mutant tissue factor compositions useful as tissue factor antagonists
US5994296A · kind A · utility
13Cited by
0References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 5, 1998 |
| Grant date | Nov 30, 1999 |
| Priority date | — |
| Expiry date | Mar 5, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention describes a mutant human tissue factor protein which binds functional Factor VII/VIIa but is substantially free of functional procoagulant cofactor activity, and compositions containing the mutant protein. Also disclosed are methods for using the mutant human tissue factor proteins, and recombinant DNA vectors for expressing the protein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.