Systematic evolution of ligands by exponential enrichment: chemi-SELEX
US5998142A · kind A · utility
29Cited by
4References
5Claims
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Key dates
| Filing date | Aug 21, 1997 |
| Grant date | Dec 7, 1999 |
| Priority date | — |
| Expiry date | Aug 21, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2541/101
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
This application provides methods for identifying nucleic acid ligands capable of covalently interacting with targets of interest. The nucleic acids can be associated with various functional units. The method also allows for the identification of nucleic acids that have facilitating activities as measured by their ability to facilitate formation of a covalent bond between the nucleic acid, including its associated functional unit, and its target.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.