Compositions for the inhibition of TNF hormone formation and uses thereof
US5998378A · kind A · utility
23Cited by
27References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 19, 1994 |
| Grant date | Dec 7, 1999 |
| Priority date | — |
| Expiry date | Apr 19, 2014 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds having proteolytic inhibitory activity useful for treating diseases, particularly as applied to the treatment of sepsis, AIDS or autoimmune diseases, resulting from a decrease in the circulating level of mature protein hormones derived from the proteolytic cleavage of prohormone precursors such as 26 kDProTNF, and methods for identifying compounds having the desired inhibitory activity are provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.