Combined preparations with vascular effect containing dihydropyridines acetylsalicylic acid nitroesters and vitamins

US5998448A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Eva Lesur · Neunburg vorm Wald, DE
• Dieter Neuser · Langenfeld, DE
• Oswald Lockhoff · Cologne, DE
• Elisabeth Perzborn · Wuppertal, DE
• Johannes-Peter Stasch · Wuppertal, DE
• Peter Kurka · Langenfeld, DE

Key dates

• Filing date: Oct 24, 1997
• Grant date: Dec 7, 1999
• Expiry date: Oct 24, 2017

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K31/621
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to new combinations of dihydropyridines of the general formula (I) ##STR1## in which R.sup.1 to R.sup.5 have the meaning indicated in the description, for the prevention and treatment of vascular disorders, in particular of cardiovascular and cerebrovascular disorders, containing dihydropyridines having calcium antagonist activity, acetylsalicylic acid nitroesters and vitamins, and, if appropriate, also further auxiliaries or active compounds.