Gro genes
US6001605A · kind A · utility
0Cited by
2References
20Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Jan 31, 1994 |
| Grant date | Dec 14, 1999 |
| Priority date | — |
| Expiry date | Jan 31, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/158
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Two novel cytokines which are involved in an inflammatory response (inflammatory cytokines) are disclosed. The inflammatory cytokines have been isolated from activated peripheral blood, preferably monocytes adhered to plastic; or peripheral blood leukocytes induced with calcium ionophore and mezerin. The two cytokines are Gro .beta. and .gamma., and their cDNA and amino acid sequences are disclosed. The expression of the genes in various cells is presented. Assay and diagnostic utilities using the cytokines; recombinant materials and procedures; purification procedures; and monoclonal antibodies to the cytokines are also shown.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.