Patent · US Expired

Synthesis of oligonucleotides

US6001982A · kind A · utility

18Cited by
15References
4Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 31, 1996
Grant dateDec 14, 1999
Priority date
Expiry dateJul 31, 2016

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07H21/00
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Synthetic processes are provided for the solution phase synthesis of oligonucleotides, especially phosphorothioate oligonucleotides, and intermediate compounds useful in the processes. Intermediates having structure ##STR1## are prepared in accord with preferred embodiments.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.