Detection of biological molecules using boronate-based chemical amplification and optical sensors
US6002954A · kind A · utility
397Cited by
30References
35Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Nov 21, 1996 |
| Grant date | Dec 14, 1999 |
| Priority date | — |
| Expiry date | Nov 21, 2016 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/66
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods are provided for the determination of the concentration of biological levels of polyhydroxylated compounds, particularly glucose. The methods utilize an amplification system that is an analyte transducer immobilized in a polymeric matrix, where the system is implantable and biocompatible. Upon interrogation by an optical system, the amplification system produces a signal capable of detection external to the skin of the patient. Quantitation of the analyte of interest is achieved by measurement of the emitted signal.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.