Antigen-carrying microparticles and their use in the induction of humoral or cellular responses
US6004763A · kind A · utility
49Cited by
0References
23Claims
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Assignee
Inventors
Key dates
| Filing date | May 12, 1998 |
| Grant date | Dec 21, 1999 |
| Priority date | — |
| Expiry date | May 12, 2018 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/815
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention concerns the use, in the induction of an immune response, of a synthetic microparticle polymer carrying on the surface one or more covalently bonded proteins capable of carrying one or more epitopes, the molecular weight of the protein(s) on the surface of the microparticles, being adjusted so as to direct the immune response to the induction of a humoral and cellular response or to the induction of a mainly cellular response, said microparticles have an average diameter of approximately 0.25 to 1.5 .mu.m.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.