Patent · US Expired

Metalloproteinase inhibitors, pharmaceutical compositions containing them, and their use

US6008243A · kind A · utility

33Cited by
8References
15Claims
0Family size

Assignees

Inventors

Key dates

Filing dateMar 25, 1997
Grant dateDec 28, 1999
Priority date
Expiry dateMar 25, 2017

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K38/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention is directed to compound of the formula I: ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, X, Y, and ##STR2## are as defined herein. These compounds are useful for inhibiting the activity of a metalloproteinase by contacting the metalloproteinase with an effective amount of the inventive compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.