Assay systems and methods for measuring P38 map kinase, and modulators thereof
US6010856A · kind A · utility
9Cited by
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14Claims
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Key dates
| Filing date | Sep 3, 1997 |
| Grant date | Jan 4, 2000 |
| Priority date | — |
| Expiry date | Sep 3, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6897
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Assay systems utilizing a reporter construct based on p38 phosphorylation of myocyte enhancer factor 2 (MEF2) transcription factor are provided. The reporter construct and methods of use are provided, as well as methods of treatment of inflammatory and muscular disorders associated with MEF2-regulated gene expression.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.