Serine protease inhibitors-cycloheptane derivatives
US6015791A · kind A · utility
14Cited by
6References
32Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 4, 1997 |
| Grant date | Jan 18, 2000 |
| Priority date | — |
| Expiry date | Dec 4, 2017 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to certain substituted oxadiazole, thiadiazole, and triazoles, in particular those including a cycloheptane structure, that are useful as serine protease inhibitors, including inhibitors for human neutrophil elastase. Compounds of the invention are useful in treating conditions such as adult respiratory distress syndrome, septic shock, and multiple organ failure.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.