Patent · US Expired

Piperazine based cytofectins

US6022874A · kind A · utility

41Cited by
10References
22Claims
0Family size

Assignee

Inventor

Key dates

Filing dateDec 23, 1998
Grant dateFeb 8, 2000
Priority date
Expiry dateDec 23, 2018

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S424/812
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present invention relates to piperazine based amphilic cationic lipids useful for gene therapy, transfection, and introducing immunogenic compounds for the purpose of vaccination. The disclosed compounds have lipophilic moieties linked to the ring nitrogens. In addition, at least one of the ring nitrogens is quatranized and linked to a hydrocarbon having at least one heteroatom.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.