Bis-platinum complexes with polyamine ligands as antitumor agents
US6022892A · kind A · utility
5Cited by
5References
21Claims
0Family size
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Key dates
| Filing date | Feb 22, 1998 |
| Grant date | Feb 8, 2000 |
| Priority date | — |
| Expiry date | Feb 22, 2018 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Bis-platinum(II) complexes with polyamine ligands, including spermidine and spermine, are disclosed. The method of making the bis-platinum(II) complexes, using a DMF complex, and the use of the bis-platinum complexes for the treatment of tumors in mammals are also disclosed. The method of making the polyamine ligands and the use of a new polyamine compound as an intermediate in the synthesis of polyamine ligands are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.