Patent · US Expired

Synthetic oligomers having chirally pure phosphonate internucleosidyl linkages mixed with non-phosphonate internucleosidyl linkages

US6028188A · kind A · utility

25Cited by

4References

23Claims

0Family size

Assignee

Genta Incorporated · US

Inventors

Lyle J. Arnold, Jr. · Poway, US
Richard I. Hogrefe · San Diego, US
Mark Reynolds · Stamford, US
Timothy A. Riley · Alameda, US
David A. Schwartz · Encinitas, US
Morteza M. Vaghefi · San Diego, US
Bob D. Brown · Littleton, US

Key dates

Filing date	Nov 21, 1994
Grant date	Feb 22, 2000
Priority date	—
Expiry date	Nov 21, 2014

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K48/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Oligomers having chirally pure phosphonate internucleosidyl linkages mixed with non-phosphonate internucleosidyl linkages which hybridize to RNA target sequences and methods for their preparation are provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.