Monoclonal antibodies against tumor-associated antigens, processes for the preparation thereof and the use thereof

US6030797A · kind A · utility

Assignee

• Dade Behring Marburg GmbH · DE

Inventors

• Klaus Bosslet · Marburg, DE
• Peter Pfleiderer · Marburg, DE
• Gerhard Seemann · Lahntal, DE

Key dates

• Filing date: Aug 7, 1998
• Grant date: Feb 29, 2000
• Expiry date: Aug 7, 2018

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2319/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to monoclonal antibodies against a tumor-associated antigen which is mainly derived from tumors from the group of carcinomas of the breast, ovaries and prostate, as well as adenocarcinomas of the lung, which additionally react with polymorphic epithelial mucin (PEM), to the preparation and use thereof and to the use of the epitope defined by the antibody for diagnosis and therapy.