Colon targeted delivery system
US6039975A · kind A · utility
204Cited by
6References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 20, 1996 |
| Grant date | Mar 21, 2000 |
| Priority date | — |
| Expiry date | Sep 20, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/2054
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A novel delivery system for targeting drugs to the colon is herein described. The system is a tablet comprised of three parts: 1) an outer enteric coating, 2) an inner semi-permeable polymer membrane containing a plasticizer and 3) a central core comprising swelling excipients and an active ingredient. The novel dosage form described herein will release the drug consistently in the colon by a time-dependent explosion mechanism. This delivery system is particularly suitable for delivering viral protease inhibitors to the colon.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.