Antibodies against human CD40
US6051228A · kind A · utility
138Cited by
4References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 19, 1998 |
| Grant date | Apr 18, 2000 |
| Priority date | — |
| Expiry date | Feb 19, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The Applicants have discovered a novel antibody, more specifically a chimerized anti-human CD40 monoclonal antibody, which blocks the interaction between gp39 and CD40. The anti-CD40 antibodies of the present invention are effective in modulating humoral immune responses against T cell-dependent antigens, collagen induced arthritis, and skin transplantation, and are also useful for their anti-inflammatory properties.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.