Inventor · Edmonds, WA, US

Alejandro A. Aruffo

30Patents
17h-index
51Co-inventors
80Inventor score

Filing activity: Jan 24, 1991 → Apr 17, 2001

Most-cited inventions

PatentTitleAreaCited byStatus
US6051228A Antibodies against human CD40 Chemistry; Metallurgy 138 Expired
US5506126A Rapid immunoselection cloning method Chemistry; Metallurgy 120 Expired
US5916560A Methods for inhibiting an immune response by blocking the GP39/CD40 and CTLA4/CD28/B7 pathways and compositions for use therewith Chemistry; Metallurgy 91 Expired
US5709859A Mixed specificity fusion proteins Emerging Cross-Sectional Technologies 75 Expired
US6210669A Methods and compositions for immunomodulation Human Necessities 71 Expired
US5849898A CD40 coding sequences Chemistry; Metallurgy 55 Expired
US5540926A Soluble and its use in B cell stimulation Chemistry; Metallurgy 55 Expired
US5993800A Methods for prolonging the expression of a heterologous gene of interest using soluble CTLA4 molecules and an antiCD40 ligand Chemistry; Metallurgy 54 Expired
US5747037A Anti-GP39 antibodies Chemistry; Metallurgy 51 Expired
US5876950A Monoclonal antibodies specific for different epitopes of human GP39 and methods for their use in diagnosis and therapy Chemistry; Metallurgy 50 Expired
US5663151A Sulfated .alpha.-glycolipid derivatives as cell adhesion inhibitors Chemistry; Metallurgy 46 Expired
US6312693A Antibodies against human CD40 Chemistry; Metallurgy 36 Expired
US5876718A Methods of inducing T cell non-responsiveness to transplanted tissues and of treating graft-versus-host-disease with anti-gp39 antibodies Chemistry; Metallurgy 32 Expired
US6376459B1 Inhibiting B cell activation with soluble CD40 or fusion proteins thereof Emerging Cross-Sectional Technologies 29 Expired
US5830731A Cloning vector, polylinker and methods Chemistry; Metallurgy 25 Expired
US6312692A Method of treating graft-versus-host disease with anti-GP39 antibodies and bone marrow cells Chemistry; Metallurgy 22 Expired
US6413514B1 Methods of using antibodies against human CD40 Chemistry; Metallurgy 22 Expired
US5597707A Tumor associated antigen recognized by the murine monoclonal antibody L6, its oligonucleotide sequence and methods for their use Physics 17 Expired
US7119183B2 Rapid immunoselection cloning method Chemistry; Metallurgy 17 Expired
US6472510B1 CD40 receptor ligands Emerging Cross-Sectional Technologies 16 Expired
US6372215B1 Monoclonal antibodies to human CD6 Emerging Cross-Sectional Technologies 13 Expired
US5945513A Fusion proteins comprising gp39 and CD8 Chemistry; Metallurgy 8 Expired
US5998172A Anti-CD6 ligand antibodies Physics 8 Expired
US6218525A Nucleic acid encoding CD28 Chemistry; Metallurgy 7 Expired
US6046314A Sp.alpha.: a novel scavenger receptor cysteine-rich domain-containing polypeptide, and monoclonal antibodies thereto Chemistry; Metallurgy 5 Expired

Source: USPTO / EPO open patent data. Inventor disambiguation is heuristic; counts are objective bibliographic measures.