Pharmaceutical compositions of bactericidal/permeability increasing protein (BPI)
US6066620A · kind A · utility
5Cited by
26References
12Claims
0Family size
Assignee
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Key dates
| Filing date | May 17, 1999 |
| Grant date | May 23, 2000 |
| Priority date | — |
| Expiry date | May 17, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Polypeptide pharmaceutical compositions having improved stability and resistance to aggregation, particle formation and precipitation comprising a polypeptide pharmaceutical and poloxamer surfactants alone, or in combination with polysorbate surfactants. Preferred polypeptides stabilized are bactericidal/permeability increasing (BPI) protein, biologically active fragments of BPI, biologically active analogs of BPI, and biologically active variants of BPI.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.