Mitogen-activated protein kinase kinase MEK6 and variants thereof
US6074862A · kind A · utility
5Cited by
1References
2Claims
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Key dates
| Filing date | Dec 20, 1995 |
| Grant date | Jun 13, 2000 |
| Priority date | — |
| Expiry date | Dec 20, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compositions and methods are provide for potentiating the activity of the mitogen-activated protein kinase p38. In particular the mitogen-activated protein kinase kinase MEK6, and variants thereof that stimulate phosphorylation of p38 are provided. Such compounds may be used, for example, for therapy of diseases associated with the p38 cascade and to identify antibodies and other agents that inhibit or activate signal transduction via p38.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.