Cloned DNA for synthesizing unique glucocerebrosidase

US6074864A · kind A · utility

Assignee

• The United States of America, as represented by the Department of Health and Human Services · US

Inventors

• Edward I. Ginns · Bethesda, US
• Brian M. Martin · Rockville, US
• Kara A. Maysak · Bethesda, US
• William K. Eliason · Reston, US
• Mary E. LaMarca · Bethesda, US

Key dates

• Filing date: Jan 13, 1994
• Grant date: Jun 13, 2000
• Expiry date: Jan 13, 2014

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Glucocerebrosidase produced by recombinant methods and having use for treatment of Gaucher's disease is disclosed. A cDNA for encoding the specific protein is taught along with the method of preparing the construct used to produce the protein.