Hepatitis A virus vaccines

US6113912A · kind A · utility

Assignee

• The United States of America, as represented by the Department of Health and Human Services · US

Inventors

• Ann W. Funkhouser · Ellicott City, US
• Suzanne U. Emerson · Rockville, US
• Robert H. Purcell · Boyds, US
• Eric D'Hondt · Ottenburg, BE

Key dates

• Filing date: Jun 7, 1995
• Grant date: Sep 5, 2000
• Expiry date: Jun 7, 2015

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A live hepatitis A virus adapted to growth in MRC-5 cells, which HAV is preferably characterized by suitable attenuation for effective vaccine administration to humans and animals without inactivation, methods for adapting HAV to growth in MRC-5, vaccine compositions and method of vaccinating humans against HAV infection.