N.gradient.2-CSF-1(long form) and carboxy truncated fragments thereof
US6117422A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Apr 21, 1995 |
| Grant date | Sep 12, 2000 |
| Priority date | — |
| Expiry date | Apr 21, 2015 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S930/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A colony stimulating factor, CSF-1, is a lymphokine useful in regulating the immune system. is a lymphokine useful in overcoming the immunosuppression induced by chemotherapy or resulting from other causes. CSF-1 is obtained in usable amounts by recombinant methods, including cloning and expression of the murine and human DNA sequences encoding this protein. Both "long" and "short" forms of this protein and muteins corresponding to the cDNA-encoded forms are disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.