Nucleic acid binders having an hydroxyamine motif
US6120997A · kind A · utility
16Cited by
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1Claims
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Assignee
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Key dates
| Filing date | Jan 13, 1998 |
| Grant date | Sep 19, 2000 |
| Priority date | — |
| Expiry date | Jan 13, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC40B40/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to the combination of hydroxyamines with nucleic acid binding motifs to generate molecules and libraries of molecules targeting specific nucleic acid sequences. In particular, a series of libraries are constructed which contain hydroxyamine functionalities that are attached to various template backbones which display varying degrees of molecular recognition to phosphodiesters and varying degrees of sequence specific recognition to nucleic acids.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.