Arylglycinamide derivatives, processes for the manufacture thereof and pharmaceutical compositions containing these compounds

US6121262A · kind A · utility

Assignee

• Boehringer Ingelheim GmbH · DE

Inventors

• Gerd Schnorrenberg · Ingelheim am Rhein, DE
• Horst Dollinger · Schemmerhofen, DE
• Franz Esser · Ingelheim am Rhein, DE
• Hans Briem · Bremen, DE
• Birgit Jung · Laupheim, DE
• Georg Speck · Ingelheim am Rhein, DE

Key dates

• Filing date: Jan 12, 1999
• Grant date: Sep 19, 2000
• Expiry date: Jan 12, 2019

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D471/10
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to new arylglycinamide derivatives of general formula I ##STR1## and the pharmaceutically acceptable salts thereof, wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and Ar have the meanings given in the specification, and the preparation and use thereof. The new compounds are valuable neurokin (tachykinin) antagonists.