Method for expression of proteins in bacterial host cells
US6127144A · kind A · utility
2Cited by
4References
14Claims
0Family size
Assignee
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Key dates
| Filing date | Oct 16, 1997 |
| Grant date | Oct 3, 2000 |
| Priority date | — |
| Expiry date | Oct 16, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/02
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
An aminopeptidase inhibitor is used when expressing heterologous protein in a bacterial host, such as Streptomyces. Use of such an inhibitor inhibits degradation of the heterologous protein by aminopeptidases. Inhibitors are designed based upon the mechanism and substrate specificity of the target protease and expressed protein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.