Inventor · Brampton, ON, CA

Lawrence T. Malek

14Patents
11h-index
17Co-inventors
65Inventor score

Filing activity: Jun 24, 1988 → Mar 18, 1999

Most-cited inventions

PatentTitleAreaCited byStatus
US5130238A Enhanced nucleic acid amplification process Emerging Cross-Sectional Technologies 903 Expired
US5409818A Nucleic acid amplification process Chemistry; Metallurgy 556 Expired
US5554517A Nucleic acid amplification process Chemistry; Metallurgy 209 Expired
US6063603A Nucleic acid amplification process Chemistry; Metallurgy 134 Expired
US5712127A Subtractive amplification Chemistry; Metallurgy 113 Expired
US5665545A Terminal repeat amplification method Chemistry; Metallurgy 88 Expired
US5466586A Method for the synthesis of ribonucleic acid (RNA) Chemistry; Metallurgy 71 Expired
US5641663A Expression system for the secretion of bioactive human granulocyte macrophage colony stimulating factor (GM-CSF) and other heterologous proteins from steptomyces Chemistry; Metallurgy 40 Expired
US5200327A Expression system for the secretion of bioactive human granulocyte macrophage colony stimulating factor (GM-CSF) and other heterologous proteins from streptomyces Chemistry; Metallurgy 17 Expired
US6498024B1 Subtractive amplification kit useful in the diagnosis of genetic disease mutation or variation Chemistry; Metallurgy 15 Expired
US5514590A Expression system comprising DNA encoding the signal peptide of protease B from Streptomyces griseus Chemistry; Metallurgy 11 Expired
US5616485A Streptomyces proteases and improved streptomyces strains for expression of peptides and polypeptides Chemistry; Metallurgy 4 Expired
US6127144A Method for expression of proteins in bacterial host cells Chemistry; Metallurgy 2 Expired
US5856166A Streptomyces proteases and methods for improved secretion of recombinantly-expressed proteins Chemistry; Metallurgy 2 Expired

Source: USPTO / EPO open patent data. Inventor disambiguation is heuristic; counts are objective bibliographic measures.