Sulfonamide inhibitors of aspartyl protease
US6127372A · kind A · utility
10Cited by
5References
23Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 1, 1996 |
| Grant date | Oct 3, 2000 |
| Priority date | — |
| Expiry date | Apr 1, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2601/08
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention provides a novel class of sulfonamide compounds of formula I which are aspartyl protease inhibitors: ##STR1## This invention also provides pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well suited for inhibiting HIV-1 and HIV-2 protease activity and consequently, may be advantageously used as anti-viral agents against the HIV-1 and HIV-2 viruses. This invention also provides methods for inhibition aspartyl protease activity and methods for treating viral infections using the compounds and compositions of this invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.