Immunotherapeutic agents
US6130226A · kind A · utility
17Cited by
1References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 18, 1999 |
| Grant date | Oct 10, 2000 |
| Priority date | — |
| Expiry date | Mar 18, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2601/08
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Cyano and carboxy derivatives of substituted styrenes are inhibitors of tumor necrosis factor .alpha., nuclear factor .kappa.B, and phosphodiesterase and can be used to combat cachexia, endotoxic shock, retrovirus replication, asthma, and inflammatory conditions. A typical embodiment is 3,3-bis-(3,4-dimethoxyphenyl)acrylonitrile.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.