Human growth hormone variants comprising amino acid substitutions
US6136563A · kind A · utility
29Cited by
12References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 24, 1998 |
| Grant date | Oct 24, 2000 |
| Priority date | — |
| Expiry date | Feb 24, 2018 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S930/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Human growth hormone variants are disclosed having enhanced affinity for the growth hormone receptor. Also disclosed are human growth hormone variants conjugated to one or more chemical groups, such as poly(ethylene glycol), which is believed to prolong the in vivo half-life of the variants.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.