Inhibitors of p38
US6147080A · kind A · utility
68Cited by
4References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 10, 1997 |
| Grant date | Nov 14, 2000 |
| Priority date | — |
| Expiry date | Jun 10, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/6561
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to inhibitors of p38, a mammalian protein kinase involved cell proliferation, cell death and response to extracellular stimuli. The compounds are of the class of pyrido [1,2-c] pyrimidin-3-one or 1,2-dihydro-pyrido [1,2-c] pyrimidin-3-one derivatives, useful as inhibitors of p38. The invention also relates to methods for producing these inhibitors. The invention also provides pharmaceutical compositions comprising the inhibitors of the invention and methods of utilizing those compositions in the treatment and prevention of various disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.