Piperidine derivative having renin inhibiting activity

US6150526A · kind A · utility

Assignee

• Hoffmann-La Roche Inc. · US

Inventors

• Alfred Binggeli · Binningen, CH
• Volker Breu · Schliengen, DE
• Daniel Bur · Therwil, CH
• Walter Fischli · Allschwil, CH
• Rolf Guller · Herznach, CH
• Georges Hirth · Colmar, FR
• Hans-Peter Marki · Basel, CH
• Marcel Muller · Frenkendorf, CH
• Christian Oefner · Glückstadt, DE
• Heinz Stadler · Basel, CH
• Eric Vieira · Frenkendorf, CH
• Maurice Wilhelm · Pfastatt, FR
• Wolfgang Wostl · Weil am Rhein, DE

Key dates

• Filing date: Dec 7, 1999
• Grant date: Nov 21, 2000
• Expiry date: Dec 7, 2019

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02P20/55
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Piperidine derivatives, their manufacture and use as medicaments, are disclosed. The invention is concerned with the piperidine derivatives of general formula I ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, Q, X, Z, m and n are as described herein.