Arylsecocholadiene derivatives

US6153605A · kind A · utility

Assignee

• Hoffmann-La Roche Inc. · US

Inventors

• Pierre Barbier · Paris, FR
• Franz Bauer · Herzogenaurach, DE
• Peter Mohr · Basel, CH
• Marc Muller · Wolfersdorf, FR
• Wolfgang Pirson · Weil am Rhein, DE

Key dates

• Filing date: Apr 16, 1998
• Grant date: Nov 28, 2000
• Expiry date: Apr 16, 2018

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07F7/1804
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Compounds of formula (I) ##STR1## as defined by the specification. The compounds are useful in the treatment or prevention of vitamin D dependent disorders, particularly psoriasis, basal cell carcinomas, disorders of keratinization and keratosis, leukemia, osteoporosis, hyperparathyroidism accompanying renal failure, transplant rejection and graft vs. host disease.