Patent · US Expired

Peptide library and screening method

US6156511A · kind A · utility

37Cited by
10References
35Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJan 21, 1998
Grant dateDec 5, 2000
Priority date
Expiry dateJan 21, 2018

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12Q1/6811
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

A random peptide library constructed by transforming host cells with a collection of recombinant vectors that encode a fusion protein comprised of a DNA binding protein and a random peptide and also encode a binding site for the DNA. binding protein can be used to screen for novel ligands. The screening method results in the formation of a complex comprising the fusion protein bound to a receptor through the random peptide ligand and to the recombinant DNA vector through the DNA binding protein.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.