Patent · US Expired

1,2,3,4-tetrahydro-benzofuro[3,2-C]pyridine derivatives

US6156757A · kind A · utility

5Cited by
1References
10Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 4, 1999
Grant dateDec 5, 2000
Priority date—
Expiry dateOct 4, 2019

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D513/04
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention concerns the compounds of formula ##STR1## the N-oxides, the pharmaceutically acceptable addition salts and the stereochemically isomeric forms thereof, wherein each R.sup.1 is independently hydrogen, halogen, C.sub.1-6 alkyl, nitro, hydroxy or C.sub.1-4 alkyloxy; Alk is C.sub.1-6 alkanediyl; n is 1 or 2; D is an optionally substituted mono-, bi- or tricyclic nitrogen containing heterocycle having central .alpha..sub.2 -adrenoceptor antagonist activity. It further relates to their preparation, compositions comprising them and their use as a medicine.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.