Antisense modulation of stat3 expression
US6159694A · kind A · utility
25Cited by
3References
23Claims
0Family size
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Inventor
Key dates
| Filing date | Apr 8, 1999 |
| Grant date | Dec 12, 2000 |
| Priority date | — |
| Expiry date | Apr 8, 2019 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/582
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds, compositions and methods are provided for inhibiting the expression of human STAT3. The compositions comprise antisense oligonucleotides targeted to nucleic acids encoding STAT3. Methods of using these oligonucleotides for inhibition of STAT3 expression and for treatment of diseases, particularly inflammatory diseases and cancers, associated with overexpression or constitutive activation of STAT3 are provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.