Serine protease inhibitors comprising .alpha.-keto heterocycles
US6159938A · kind A · utility
67Cited by
8References
77Claims
0Family size
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Key dates
| Filing date | May 20, 1997 |
| Grant date | Dec 12, 2000 |
| Priority date | — |
| Expiry date | May 20, 2017 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided are methods of inhibiting the activity of a serine protease using protease inhibitors that include an alpha-keto heterocycle in their structure. The methods are useful in the treatment of ischemic heart or treatment of symptoms associated with blood coagulation disorders. Also provided are methods for detecting or quantifying the activity of a serine protease in a pure sample.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.