Isolation and characterization of cDNAs coding for the .alpha., .beta., and .gamma. subunits of the high-affinity receptor for immunoglobulin E

US6165744A · kind A · utility

Assignee

• The United States of America, as represented by the Department of Health and Human Services · US

Inventors

• Jean-Pierre Kinet · Bethesda, US
• Henry Metzger · Bethesda, US

Key dates

• Filing date: Dec 14, 1990
• Grant date: Dec 26, 2000
• Expiry date: Dec 14, 2010

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K14/70535
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The present invention relates to DNA segments encoding the .alpha., .beta., and .gamma. subunits of the high affinity receptor for immunoglobulin E (IgE). The invention further relates to a method of producing the receptor by expressing cDNA for its .alpha., .beta., and .gamma. subunits in a host cell simultaneously.