Method of expressing an exogenous nucleic acid
US6165754A · kind A · utility
5Cited by
9References
44Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 8, 1999 |
| Grant date | Dec 26, 2000 |
| Priority date | — |
| Expiry date | Jun 8, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2750/14143
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a method of expressing an exogenous nucleic acid in a mammal. The method comprises non-systemically administering to a non-neuronal tissue of said mammal an exogenous nucleic acid operatively linked to a promoter. The exogenous nucleic acid is proximal to at least one native parvoviral inverted terminal repeat and does not require encapsidation. The expression of the exogenous nucleic acid in the tissue is not substantially diminished at 28 days after administration of the exogenous nucleic acid.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.