Inventor · Potomac, MD, US

Ronald G. Crystal

35Patents
14h-index
46Co-inventors
81Inventor score

Filing activity: Nov 24, 1989 → Jul 13, 2020

Most-cited inventions

PatentTitleAreaCited byStatus
US6322536A Minimally invasive gene therapy delivery and method Human Necessities 146 Expired
US6508802B1 Remote sensing gene therapy delivery device and method of administering a therapeutic solution to a heart Human Necessities 125 Expired
US5837511A Non-group C adenoviral vectors Chemistry; Metallurgy 122 Expired
US5869037A Adenoviral-mediated gene transfer to adipocytes Chemistry; Metallurgy 98 Expired
US5997509A Minimally invasive gene therapy delivery device and method Human Necessities 69 Expired
US6127525A Chimeric adenoviral coat protein and methods of using same Chemistry; Metallurgy 55 Expired
US6013638A Adenovirus comprising deletions on the E1A, E1B and E3 regions for transfer of genes to the lung Chemistry; Metallurgy 53 Expired
US5618786A Aerosolization of protein therapeutic agent Human Necessities 33 Expired
US5928944A Method of adenoviral-medicated cell transfection Chemistry; Metallurgy 32 Expired
US5238683A Aerosol preparation of glutathione and a method for augmenting glutathione level in lungs Human Necessities 29 Expired
US6153435A Nucleic acid that encodes a chimeric adenoviral coat protein Chemistry; Metallurgy 26 Expired
US9066966B2 Methods and pharmaceutical compositions for the treatment of cardiomyopathy due to friedreich ataxia Chemistry; Metallurgy 24 Active
US6159950A Method of modulating hair growth Human Necessities 18 Expired
US5989521A Method for augmenting a decreased level of reduced glutathione in the lung Human Necessities 15 Expired
US6329348A Method of inducing angiogenesis Human Necessities 13 Expired
US10337027B2 Methods and pharmaceutical compositions for the treatment and the prevention of cardiomyopathy due to Friedreich ataxia Chemistry; Metallurgy 12 Active
US9682133B2 Disrupted adenovirus-based vaccine against drugs of abuse Chemistry; Metallurgy 8 Active
US6165754A Method of expressing an exogenous nucleic acid Chemistry; Metallurgy 5 Expired
US6518255B2 Multiple site delivery of adenoviral vector directly into muscle for the induction of angiogenesis Human Necessities 4 Expired
US6682728B1 Efficient and selective adenoviral-mediated gene transfer into vascular neointima Chemistry; Metallurgy 3 Expired
US12122844B2 Treatment of brain cancers using central nervous system mediated gene transfer of monoclonal antibodies Chemistry; Metallurgy 2 Active
US10946094B2 Adenoassociated viral mediated persistant anti-VEGF therapy for ovarian cancer Chemistry; Metallurgy 1 Active
US11821009B2 Genetic modification of the AAV capsid resulting in altered tropism and enhanced vector delivery Chemistry; Metallurgy 1 Active
US6939540B1 Method of enhancing bone density Chemistry; Metallurgy 1 Expired
US12024568B2 Treatment of brain cancers using central nervous system mediated gene transfer of monoclonal antibodies Chemistry; Metallurgy 1 Active

Source: USPTO / EPO open patent data. Inventor disambiguation is heuristic; counts are objective bibliographic measures.