Liquid chromatography column

US6171486A · kind A · utility

Assignee

• Dyax Corp. · US

Inventors

• Jeffrey R. Green · San Francisco, US
• Jeffrey A. Kaster · Blacksburg, US
• Victor R. Lancaster · Los Gatos, US
• Peter J. Leavesley · Charlottesville, US
• Gary L. McNeil · Allegan, US
• Thomas C. Ransohoff · Lexington, US
• Peter C. Van Davelaar · Maidens, US

Key dates

• Filing date: Nov 12, 1998
• Grant date: Jan 9, 2001
• Expiry date: Nov 12, 2018

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2030/8881
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A chromatography cartridge assembly includes a cartridge and first and second end caps. A wall of the cartridge defines a chamber for containing chromatography media. The end caps define inlet and outlet passages, respectively, for flow of process fluid. The first end cap defines flow distributor passages for distributing process fluid across a cross-sectional area of the chamber, and the second end cap defines flow collector passages for collecting process fluid from across a cross-sectional area of the chamber. A clamp is circumferentially located about the cartridge wall for applying a radial load through the wall to the first end cap to fix the first end cap in a desired position.