Patent assignee · US · COMPANY

Dyax Corp.

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176Patents
106Active
176Granted
50Portfolio score

Filing activity: Mar 10, 1994 → Oct 7, 2019 · 42 expiring within 5 years

Most-cited patents

PatentTitleAreaCited byStatus
US5837500A Directed evolution of novel binding proteins Chemistry; Metallurgy 278 Expired
US5663143A Engineered human-derived kunitz domains that inhibit human neutrophil elastase Human Necessities 86 Expired
US6451260B1 Method for producing microporous elements, the microporous elements thus produced and uses thereof Physics 71 Expired
US7208293B2 Directed evolution of novel binding proteins Chemistry; Metallurgy 67 Expired
US6423498B1 Variegated Kunitz domain peptide library and uses thereof Chemistry; Metallurgy 65 Expired
US5795865A "Kallikrein-inhibiting ""kunitz domain"" proteins and analogues thereof" Human Necessities 61 Expired
US6979538B2 Directed evolution of novel binding proteins Chemistry; Metallurgy 61 Expired
US7118879B2 Method of recovering a nucleic acid encoding a proteinaceous binding domain which binds a target material Chemistry; Metallurgy 59 Expired
US6171486A Liquid chromatography column Physics 57 Expired
US7235530B2 Kallikrein inhibitors and anti-thrombolytic agents and uses thereof Human Necessities 52 Expired
US6333402A "Kallikrein-binding ""Kunitz domain"" proteins and analogues thereof" Human Necessities 51 Expired
US5601708A Apparatus for pressurizing a removable chromatography cartridge Physics 47 Expired
US6057287A "Kallikrein-binding ""Kunitz domain"" proteins and analogues thereof" Physics 46 Expired
US6010880A Inhibitors of human plasmin derived from the kunitz domains Chemistry; Metallurgy 45 Expired
US5994125A "Kallikrein-inhibiting ""Kunitz Domain"" proteins and analogues thereof" Human Necessities 44 Expired
US6071723A Inhibitors of human plasmin derived from the Kunitz domains Chemistry; Metallurgy 41 Expired
US7064107B2 Prevention and reduction of blood loss Chemistry; Metallurgy 40 Expired
US7166576B2 Methods for preserving organs and tissues Human Necessities 39 Expired
US6103499A Inhibitors of human plasmin derived from the Kunitz domains Chemistry; Metallurgy 39 Expired
US7329737B2 Antibodies that bind hK-1 Physics 36 Expired
US7718617B2 Methods for preserving organs and tissues Human Necessities 33 Active
US7153829B2 Kallikrein-inhibitor therapies Human Necessities 31 Expired
US7276480B1 Prevention and reduction of blood loss Chemistry; Metallurgy 31 Expired
US6984373B2 Fibrin binding moieties useful as imaging agents Physics 30 Expired
US8124586B2 Prevention and reduction of blood loss Chemistry; Metallurgy 30 Active

Source: USPTO / EPO open patent data. Counts and citation impact are objective bibliographic measures.