Nucleic acid ligand inhibitors to DNA polymerases
US6183967A · kind A · utility
40Cited by
19References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 1, 1999 |
| Grant date | Feb 6, 2001 |
| Priority date | — |
| Expiry date | Mar 1, 2019 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/96433
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
This invention discloses high-affinity oligonucleotide ligands to the thermostable Taq polymerase, Tth polymerase and TZ05 polymerase. Specifically, this invention discloses DNA ligands having the ability to bind to the Taq, Tth and TZ05 polymerases and the methods for obtaining such ligands. The ligands are capable of inhibiting polymerases at any predetermined temperature.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.