Pyrazolopyrimidine and pyrazolines and process for preparation thereof
US6194410A · kind A · utility
21Cited by
1References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 24, 1999 |
| Grant date | Feb 27, 2001 |
| Priority date | — |
| Expiry date | Feb 24, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D495/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is concerned with pyrazolopyrimidines and pyrazolotriazines of the general formula ##STR1## and their pharmaceutically acceptable salts. Surprisingly, these compounds evidence selective affinity to 5HT-6 receptors. They are accordingly suitable for use in the treatment and prevention of central nervous disorders such as, for example, psychoses, schizophrenia, manic depressions, depressions, neurological disorders, memory disorders, Parkinson's disease, amyotrophic lateral sclerosis, Alzheimer's disease and Huntington's chorea.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.