Lipid-conjugated polyamide compounds and related compositions and methods thereof
US6197332A · kind A · utility
9Cited by
1References
25Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 12, 1998 |
| Grant date | Mar 6, 2001 |
| Priority date | — |
| Expiry date | Aug 12, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/645
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
In accordance with the present invention, there are provided lipid-conjugated polyamide compounds and related compositions and methods thereof. Lipid-conjugated polyamide compounds of the present invention are particularly useful as vehicles for delivering biologically active agents to a target site. In particular, the invention compounds are effective at facilitating the delivery of polynucleotides to cells. The present invention also provides a method for producing stable formulations of polynucleotides complexed with a delivery vehicle.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.