1- (1,2-disubstituted piperidinyl) -4-substituted piperazine derivatives

US6197772A · kind A · utility

Assignee

• Janssen Pharmaceutica NA · BE

Inventors

• Frans Eduard Janssens · Bonheiden, BE
• François Maria Sommen · Wortel, BE
• Dominique Louis Nestor Ghislain Surleraux · Braine-le-Comte, BE
• Joseph Elisabeth Leenaerts · Rijkevorsel, BE
• Yves Emiel Maria Van Roosbroeck · Heist-op-den-Berg, BE

Key dates

• Filing date: Apr 3, 1998
• Grant date: Mar 6, 2001
• Expiry date: Apr 3, 2018

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02P20/55
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention concerns the compounds of formula ##STR1## the N-oxide forms, the pharmaceutically acceptable addition salts and the stereoisomeric forms thereof, as substance-P antagonists; their preparation, compositions containing them and their use as a medicine.